Painel Adipocina Sérica de Camundongo

Descrição: Mouse Serum Adipokine Panel
Informação: Este ensaio multiplex é destinado a dosagem de Leptina, Resistina, IL-6, TNFα, MCP-1, PAI-I e Insulina em amostras de soro ou plasma de camundongo.
Aplicações: Ensaio Overnight.
Reatividade: Camundongo
Precisão, %:
  • Inter-ensaio: <12
  • Intra-ensaio: <5
Sensibilidade:
  • Leptina: 3.7 pg/mL
  • Resistina: 1.6 pg/mL
  • IL-6: 1.7 pg/mL
  • TNFα: 2.5 pg/mL
  • MCP-1: 7.8 pg/mL
  • PAI-1: 19.4 pg/mL
  • Insulina: 24.9 pg/mL
Áreas Terapêuticas:
  • Diabetes
  • Obesidade
  • Desordens Metabólicas
Exatidão:
  • Leptina 101%
  • Resistina 104%
  • IL-6 105%
  • TNFα 95%
  • MCP-1 99%
  • PAI-1 105%
  • Insulina 95%

Intervalo de Curva Padrão:

  • 16–50,000 pg/mL
Configuração: 7 Plex
 
Analitos Disponíveis:
  • IL-6
  • Insulina
  • Leptina
  • MCP-1
  • Resistina
  • TNF-α
  • PAI-1 (Total)
 
Método de Detecção: Luminex xMAP
 
Tipo de Ensaio: Multiplex 

Instruções de Uso

 

Referências

  • Activity of the histone deacetylase inhibitor FR235222 on Toxoplasma gondii: inhibition of stage conversion of the parasite cyst form and study of new derivative compounds.
    Maubon D, Bougdour A, Wong YS, Brenier-Pinchart MP, Curt A, Hakimi MA, Pelloux H (2010) Antimicrob Agents Chemother.54:4843-50. Epub 2010 Aug 16.

    •  

  • Prenatal androgen exposure programs metabolic dysfunction in female mice.
    Roland AV, Nunemaker CS, Keller SR, Moenter SM (2010) J Endocrinol

    •  

  • Placenta growth factor (PlGF), a novel inducer of plasminogen activator inhibitor-1 (PAI-1) in sickle cell disease (SCD).
    Patel N, Sundaram N, Yang M, Madigan C, Kalra VK, Malik P (2010) J Biol Chem

    •  

  • Lack of SIRT1 (Mammalian Sirtuin 1) Activity Leads to Liver Steatosis in the SIRT1+/- Mice: A Role of Lipid Mobilization and Inflammation.
    Xu F, Gao Z, Zhang J, Rivera CA, Yin J, Weng J, Ye J (2010) Endocrinology

    •  

  • Age-accelerated atherosclerosis correlates with failure to upregulate antioxidant genes.
    Alan R Collins, Christopher J Lyon, Xuefeng Xia, Joey Z Liu, Rajendra K Tangirala, Fen Yin, Rima Boyadjian, Alfiya Bikineyeva, Domenico Praticò, David G Harrison, Willa A Hsueh (2009) Circulation research.104:e42-54

    •  

  • HSP72 protects against obesity-induced insulin resistance.
    Jason Chung, Anh-Khoi Nguyen, Darren C Henstridge, Anna G Holmes, M H Stanley Chan, Jose L Mesa, Graeme I Lancaster, Robert J Southgate, Clinton R Bruce, Stephen J Duffy, Ibolya Horvath, Ruben Mestril, Matthew J Watt, Philip L Hooper, Bronwyn A Kingwell, Laszlo Vigh, Andrea Hevener, Mark A Febbraio (2008) Proceedings of the National Academy of Sciences of the United States of America.105:1739-44

    •  

  • Effects of dietary fibers on weight gain, carbohydrate metabolism, and gastric ghrelin gene expression in mice fed a high-fat diet.
    Zhong Q Wang, Aamir R Zuberi, Xian H Zhang, Jacalyn Macgowan, Jianhua Qin, Xin Ye, Leslie Son, Qinglin Wu, Kun Lian, William T Cefalu (2007) Metabolism: clinical and experimental.56:1635-42

    •  

  • Improved glucose tolerance in mice receiving intraperitoneal transplantation of normal fat tissue.
    D Konrad, A Rudich, E J Schoenle (2007) Diabetologia.50:833-9

    •  

  • Recombinant leptin promotes atherosclerosis and thrombosis in apolipoprotein E-deficient mice.
    Peter F Bodary, Shufang Gu, Yuechun Shen, Alyssa H Hasty, Joshua M Buckler, Daniel T Eitzman (2005) Arteriosclerosis, thrombosis, and vascular biology.25:e119-22

    •  

    Somente para pesquisa, não é destinado ao uso terapêutico ou diagnóstico.

     

     
    Código do ProdutoMADPK-71K
    Tipo de Produto Multiplex MILLIPLEX - Endócrino Adipócito/Adipoquinas
    Fornecedor MILLIPORE
    Quantidade96 testes
    EspécieCamundongo
    Clique aqui para mais informações
    Solicitar Cotação