Painel Endócrino de Camundongo
Descrição: MILLIPLEX MAP Mouse Endocrine Panel
MILLIPLEX MAP Mouse Endocrine PanelInformação: este ensaio multiplex é destinado a quantificação simultânea dos seguintes hormônios de camundongo/rato em qualquer combinação: Insulina, Amilina, Leptina, Glucagon, and GLP-1.
Aplicação: 10 µL de amostra. Ensaio overnight.
Reatividade: Camundongo
Precisão, %:
- Inter-ensaio: 4.8–20.7
- Intra-ensaio: 3.8–10.6
Sensibilidade:
≤ 6.2 pM
Áreas Terapêuticas:
- Diabetes
- Obesidade
- Desordem Metabólica
Exatidão:
- Recuperação em Matrix Sérica: Insulina 100.3%
- Amilina 101.0%
- Leptina 100.5%
- Glucagon 99.7%
- GLP-1 101.1%
- Recuperação e Amostras de Soro: Insulina 105.8%
- Amilina 80.2%
- Leptina 96.5%
- Glucagon 105.9%
- GLP-1 115.2%
Intervalo de Curva Padrão:
6.2–4,500 pM
Analito Disponível:
- Insulina
- Leptina
- Amilina (Active)
- GLP-1 (Active)
- Glucagon
Método de Detecção: Luminex xMAP
Linearidade de Diluição:
79–100%
Tipo de Ensaio: Multiplex
*Somente para pesquisa, não é destinado ao uso terapêutico ou diagnóstico
DOCUMENTO
REFERÊNCIAS PARA ESTE KIT
- Obese reversal by a chronic energy restricted diet leaves an increased Arc NPY/AgRP, but no alteration in POMC/CART, mRNA expression in diet-induced obese mice.
Yu Y, Deng C, Huang XF (2009) Behavioural brain research.205:50-56 - Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin resistant mouse models----Association with liver and adipose tissue effects.
Xu J, Stanislaus S, Chinookoswong N, Lau YY, Hager T, Patel J, Ge H, Weiszmann J, Lu SC, Graham M, Busby J, Hecht R, Li YS, Li Y, Lindberg RA, Veniant MM (2009) American journal of physiology. Endocrinology and metabolism - Energy-restricted pair-feeding normalizes low levels of brain-derived neurotrophic factor/tyrosine kinase B mRNA expression in the hippocampus, but not ventromedial hypothalamic nucleus, in diet-induced obese mice.
Y Yu, Q Wang, X-F Huang (2009) Neuroscience.160:295-306 - Differential expression of hypothalamic CART mRNA in response to body weight change following different dietary interventions.
Yinghua Yu, Tim South, Qing Wang, Xu-Feng Huang (2008) Neurochemistry international.52:1422-30 - Runt-related transcription factor 2 (RUNX2) and RUNX2-related osteogenic genes are down-regulated throughout osteogenesis in type 1 diabetes mellitus.
John L Fowlkes, R Clay Bunn, Lichu Liu, Elizabeth C Wahl, Hannah N Coleman, Gael E Cockrell, Daniel S Perrien, Charles K Lumpkin, Kathryn M Thrailkill (2008) Endocrinology.149:1697-704 - Generation and characterization of two novel mouse models exhibiting the phenotypes of the metabolic syndrome: Apob48-/-Lepob/ob mice devoid of ApoE or Ldlr.
David J Lloyd, Jocelyn McCormick, Joan Helmering, Ki Won Kim, Minghan Wang, Preston Fordstrom, Stephen A Kaufman, Richard A Lindberg, Murielle M Véniant (2008) American journal of physiology. Endocrinology and metabolism.294:E496-505 - Oxidative stress contributes to aging by enhancing pancreatic angiogenesis and insulin signaling.
Gaëlle Laurent, Florence Solari, Bogdan Mateescu, Melis Karaca, Julien Castel, Brigitte Bourachot, Christophe Magnan, Marc Billaud, Fatima Mechta-Grigoriou (2008) Cell metabolism.7:113-24 - Improved glucose tolerance in mice receiving intraperitoneal transplantation of normal fat tissue.
D Konrad, A Rudich, E J Schoenle (2007) Diabetologia.50:833-9
Brochura
MILLIPLEX MAP and the Endocrine System Luminex xMAP Technology| Código do Produto | MENDO-75K |
|---|---|
| Tipo de Produto | Multiplex MILLIPLEX - Endócrino Endócrino |
| Fornecedor | MILLIPORE |
| Quantidade | 96 testes  |
| Espécie | Camundongo |
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