Leptina de Rato - RIE
Rat Leptin RIA.
Leptina é sintetizada nos adipócitos como uma molécula de 16kD e seus níveis circulantes é diretamente proporcional a quantidade total de gordura corpórea.
Aplicações:
Ensaio de equilíbrio overnight, incubação a temperatura ambiente. Volume de Amostra < 100 µL, soro, plasma ou meio de cultura de tecido.
Reatividade: Rato
Precisão, %:
- Inter-ensaio: 3.0–5.7
- Intra-ensaio: 2.0–4.6
Áreas terapêuticas:
- Diabetes
- Obesidade
- Desordem Metabólica
Exatidão: 92–103%
Intervalo da curva: 0.5–50 ng/mL
Reatividade Cruzada:
Leptina de Rato 100% / Leptina de Camundongo / Leptina de Camundongo 100% / Insulina - Não Detectável / Leptina Humana <2% / Glucagon - Não detectável / SRIF - Não detectável / Leptina canina 0.5%
UniProt Number:
- P48357
- P50596
Linearidade de Diluição: 78–96%
Desempenho:
- ED<sub>80</sub> = 1.0 ± 0.1 nh/ml
- ED<sub>50</sub> = 3.1 ± 0.2 ng/ml
- ED<sub>20 = 9.9 ± 1.0 ng/ml
Proteína: Leptina (Obese Protein, OB)
Somente para pesquisa, não é destinado ao uso terapêutico ou diagnóstico.
Documento
REFERÊNCIA
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Glutamate permeability at the blood-brain barrier in insulinopenic and insulin-resistant rats.
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Overfeeding-induced obesity in spontaneously hypertensive rats: an animal model of the human metabolic syndrome.
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Dietary modulation of ghrelin and leptin and gorging behavior after weight loss in the obese Zucker rat.
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Short-term physiological hyperleptinemia decreases arterial blood pressure.
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Dietary L-arginine supplementation reduces white fat gain and enhances skeletal muscle and brown fat masses in diet-induced obese rats.
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Gestational weight gain by reduced brain melanocortin activity affects offspring energy balance in rats.
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Moderate daily exercise activates metabolic flexibility to prevent prenatally induced obesity.
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Early undernutrition leads to long-lasting reductions in body weight and adiposity whereas increased intake increases cardiac fibrosis in male rats.
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No effect of dietary calcium on body weight of lean and obese mice and rats.
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Chronic MCH-1 receptor modulation alters appetite, body weight and adiposity in rats.
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Decreased leptin uptake in hypothalamic nuclei with ageing in Wistar rats.
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Proinflammatory role of leptin in experimental colitis in rats benefit of cholecystokinin-B antagonist and beta3-agonist.
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Effects of fructose and glucose on plasma leptin, insulin, and insulin resistance in lean and VMH-lesioned obese rats.
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A1 adenosine receptor activation increases adipocyte leptin secretion.
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| Código do Produto | RL-83K |
|---|---|
| Tipo de Produto | RIE Obesidade e Diabetes Leptina |
| Fornecedor | MILLIPORE |
| Quantidade | 250 testes ![]() |
| Espécie | Rato |
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